منابع مشابه
Synthetic biology meets tissue engineering
Classical tissue engineering is aimed mainly at producing anatomically and physiologically realistic replacements for normal human tissues. It is done either by encouraging cellular colonization of manufactured matrices or cellular recolonization of decellularized natural extracellular matrices from donor organs, or by allowing cells to self-organize into organs as they do during fetal life. Fo...
متن کاملSynthetic tissue biology: tissue engineering meets synthetic biology.
We propose the term "synthetic tissue biology" to describe the use of engineered tissues to form biological systems with metazoan-like complexity. The increasing maturity of tissue engineering is beginning to render this goal attainable. As in other synthetic biology approaches, the perspective is bottom-up; here, the premise is that complex functional phenotypes (on par with those in whole met...
متن کاملSynthetic meets cell biology
Following a successful panel discussion at last years' American Society for Cell Biology Annual Meeting, the first minisymposium in Synthetic Cell Biology was held at this years' annual meeting in Denver. This is an exciting first for the society, and the attendance clearly supported the interest of cell biologists in applying the concepts of synthetic biology to the understanding and engineeri...
متن کاملControl theory meets synthetic biology.
The past several years have witnessed an increased presence of control theoretic concepts in synthetic biology. This review presents an organized summary of how these control design concepts have been applied to tackle a variety of problems faced when building synthetic biomolecular circuits in living cells. In particular, we describe success stories that demonstrate how simple or more elaborat...
متن کاملSynthetic biology and regulatory networks: where metabolic systems biology meets control engineering.
Metabolic pathways can be engineered to maximize the synthesis of various products of interest. With the advent of computational systems biology, this endeavour is usually carried out through in silico theoretical studies with the aim to guide and complement further in vitro and in vivo experimental efforts. Clearly, what counts is the result in vivo, not only in terms of maximal productivity b...
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ژورنال
عنوان ژورنال: Biochemical Society Transactions
سال: 2016
ISSN: 0300-5127,1470-8752
DOI: 10.1042/bst20150289